Will opting-in for sync licensing affect other licensing arrangements I have in place with other companies?

CD Baby's music licensing services are non-exclusive (meaning you can work with other agencies too!)
You should verify with the other sync licensing companies. If you have an exclusive deal with another company, yes, it will interfere. If you have a non-exclusive deal with another sync company there shouldn’t be any problems.

However, the YouTube and Facebook Monetization portion of our Licensing program IS EXCLUSIVE, so you need to make sure that you haven’t granted those particular rights to anyone else.